SAMe 97540-22-2 Research raw material

Basic Chemical Information

Product Introduction

SAMe (full name: S-Adenosyl-L-Methionine Disulfate Tosylate, Chinese name: Ademetionine disulfate tosylate) is a key physiological methyl donor in organisms and a core tool small molecule for epigenetics and metabolic regulation in scientific research. The research-grade SAMe universally adopts disulfate tosylate complex salt configuration, which effectively solves the defects of free ademetionine such as poor stability, easy degradation and activity loss. It features highly stable molecular structure, uniform methyl transfer activity and ultra-low impurity content. The material presents pure loose white crystalline powder texture without agglomeration or visible foreign matter under normal conditions. Long-term low-temperature, dark and dry storage preserves complete molecular structure and specific methyl donor activity with excellent batch consistency and in-vitro biochemical experiment repeatability, suitable for various metabolic and epigenetic research systems.

Application Scope

Epigenetic Methylation Mechanism Research：As a classic in-vitro methyl donor tool compound, it is stably applied to in-vitro induction experiments of DNA, RNA and histone methylation modification, methyltransferase activity verification and epigenetic pathway regulation mechanism analysis. It features stable methyl transfer efficiency and high experimental repeatability, serving as a core experimental material for basic epigenetic research.

Liver Protection and Hepatocyte Repair Mechanism Research：As a core research tool for maintaining hepatocyte metabolic homeostasis, SAMe participates in key pathways including hepatocyte methylation modification, cell membrane phospholipid synthesis and remodeling, and glutathione antioxidant system activation relying on its potent methyl donor activity. It can be applied to intervention experiments on in-vitro liver injury models (oxidative stress injury, metabolic liver injury, toxic liver injury) to explore the molecular mechanisms of SAMe regulating hepatocyte proliferation, apoptosis inhibition and injury repair. It is also suitable for basic research on liver fibrosis, hepatocyte lipid metabolism disorder and hepatic endotoxin clearance. It serves as a key experimental material for verification of liver protection and hepatocyte repair target mechanisms and screening of liver-protective lead drugs with stable dose-gradient response and high experimental data repeatability.

Antidepressant and Mood Regulation Mechanism Research： As a key endogenous functional molecule for central mood regulation, SAMe participates in the synthesis and metabolic regulation of mood-related monoamine neurotransmitters such as dopamine, serotonin and norepinephrine through the central methylation modification pathway, improving central neurotransmitter disorder. It is suitable for the construction of in-vitro neuronal depression models and research on cellular mechanisms of mood disorders. It can verify the mechanism of SAMe in regulating synaptic plasticity, alleviating neuronal damage and improving mood-related metabolic abnormalities, and is widely applied in basic antidepressant pharmacological research, mood homeostasis mechanism analysis and R&D of novel mood-improving small-molecule drugs with clear target effects and extremely low experimental interference.

Academic Experiment Reproduction & System Control：Its physicochemical parameters, water solubility and methyl donor activity fully conform to international standard research-grade materials, enabling accurate reproduction of published in-vitro cellular metabolic intervention, methylation modification induction and antioxidant activity verification experiments for academic research deepening, metabolic biochemical experimental system calibration and research data verification.

Metabolic Regulation Lead Drug Screening & Derivation： With excellent biocompatibility and clear methylation functional sites, it serves as a lead intermediate for metabolic regulation, liver protection and nerve repair, supporting structure-activity relationship analysis, derivative screening and structural optimization of novel metabolic small-molecule drugs.

Important Disclaimer

This product is a methyl donor and metabolic regulatory complex salt small-molecule intermediate for pure scientific research, only used as laboratory chemical material. It is not drug, veterinary drug, health product, food or cosmetic raw material with no medical, commercial or civilian value and no therapeutic or health-care effects.

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