Cenobamate 913088-80-9 Research raw material

Basic Chemical Information

Product Introduction

Cenobamate (Chinese name: Cenobamate, aliases: YKP3089) is a novel small-molecule compound with dual neuromodulatory mechanisms, acting on both voltage-gated sodium channels and γ-aminobutyric acid (GABA) receptor systems. It serves as a core dedicated research tool substrate for the study of central neuronal excitability balance, anticonvulsant pharmacology, epilepsy mechanisms and neural homeostasis regulation. Featuring a stable molecular skeleton with chlorophenyl and tetrazole active structures, uniform high purity and extremely low impurity content, the material presents pure loose crystalline texture without agglomeration or visible foreign matter under normal conditions. It maintains stable physicochemical properties at room temperature and pressure and resists mild environmental oxidation. Long-term dark, dry and constant-temperature storage preserves complete molecular structure and specific neuromodulatory activity with excellent batch consistency and in-vitro experimental repeatability.

Application Scope

Voltage-Gated Sodium Channel Regulation Research：As a classic sodium channel inhibitory tool compound, it is stably applied to in vitro neuronal sodium channel activity detection, abnormal high-frequency discharge inhibition verification and channel kinetic regulation mechanism analysis. It effectively reduces neuronal hyperexcitability with clear target effects and high experimental repeatability, serving as a core experimental material for neuronal excitability pharmacological research.

GABAergic Inhibitory Neural Pathway Research：It is used for in vitro GABA receptor function regulation experiments, inhibitory neurotransmitter signal transduction enhancement mechanism analysis and central nerve homeostasis balance mechanism verification, suitable for basic research on cellular-level neural inhibitory function intervention and convulsion-related pathological mechanisms with stable linear dose-gradient response and reliable experimental data.

Anticonvulsant and In-Vitro Epilepsy Model Research： Based on its dual neuromodulatory activity, it is applied to in-vitro epileptiform discharge cell model construction, neuronal abnormal excitatory damage mechanism research and anticonvulsant target pharmacological verification, suitable for basic in vitro research on refractory epilepsy mechanism analysis and neuroprotective pharmacology.

Academic Experiment Reproduction & System Control： Its physicochemical parameters, organic solubility and dual neuromodulatory activity fully conform to international standard research-grade materials, enabling accurate reproduction of published in vitro neuronal intervention experiments, ion channel function verification experiments and anticonvulsant activity gradient tests for academic research deepening, neuropharmacological experimental system calibration and research data verification.

Novel Neuromodulatory Drug Derivation & Screening：With modifiable active sites including tetrazole heterocycle, chlorinated aromatic ring and carbamate groups, it features strong molecular transformation potential. As a lead intermediate for novel anti-epileptic and neural homeostasis regulation drugs, it supports structure-activity relationship analysis, derivative screening and optimization, and R&D of neuroprotective small-molecule drugs.

Important Disclaimer

Any use for human or animal in-vivo administration, clinical trials, pharmaceutical preparation production, raw material processing, food and cosmetic addition, commercial blending and civilian circulation is strictly prohibited. This product is a neuromodulatory and anticonvulsant organic small-molecule intermediate for pure scientific research, only used as laboratory chemical material. It is not drug, veterinary drug, health product, food or cosmetic raw material with no medical, commercial or civilian value and no therapeutic or health-care effects.

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