Iguratimod 123663-49-0 pharmaceutical intermediate

Basic Chemical Information

Product Introduction

Iguratimod (alias T614) is a small-molecule heterocyclic organic compound based on the benzopyran core, serving as a dedicated research substrate for inflammation and immune mechanism studies. It features a highly specific and stable molecular skeleton with balanced and controllable physicochemical properties. The material presents uniform and pure morphology under normal conditions, with excellent lipophilicity, structural stability and degradation resistance. It is not prone to oxidation, deliquescence or discoloration at room temperature, maintaining stable molecular activity and structural integrity during long-term storage.As a widely adopted experimental material in the fields of immunomodulation and anti-inflammatory mechanism research, this molecule possesses specific target affinity and broad substrate adaptability, stably applicable to various refined in vitro research systems at cellular, molecular and biochemical levels.

Application Scope 

Inflammation & Immune Mechanism Research： It selectively targets COX-2 without interfering with COX-1 pathways, and regulates the expression of inflammatory factors such as IL-1, IL-6, IL-8 and TNF-α. It is widely used for in vitro inflammatory model construction, immune cell activity regulation and inflammatory signaling pathway analysis with high target specificity and experimental repeatability.

Molecular Target Pharmacological Research： It is applied to in vitro affinity testing, activity inhibition experiments and dose-response studies of key targets including MIF and COX-2, serving as a classic in vitro tool compound for basic research on small-molecule inhibitor pharmacological mechanisms.

Organic Synthesis & Structural Derivation R&D： With a typical benzopyrone core structure and accessible functional groups, it features strong structural plasticity. As a core synthetic intermediate, it supports structural modification, group decoration and new lead compound screening for similar anti-inflammatory and immunomodulatory heterocyclic derivatives.

Academic Experiment Reproduction & System Control： Its physicochemical properties are fully consistent with international standard research materials, enabling accurate reproduction of published in vitro cell experiments, molecular biochemical tests and target inhibition assays for academic research deepening and experimental data verification.

Structural Stability Special Research： Based on its excellent thermal stability and oxidation resistance, it supports research on molecular structural evolution and degradation rules under light, temperature fluctuation and acid-base conditions for compound property and stability analysis.

Important Disclaimer

This product is an organic chemical intermediate for pure scientific research, only used as laboratory chemical material. It is not drug, veterinary drug, health product, food or cosmetic raw material with no medical, commercial or civilian value and no therapeutic or health-care effects. Purchasers confirm the purpose of formal laboratory scientific research and promise not to change the use. All risks and legal liabilities arising from illegal misappropriation and abuse shall be borne independently by purchasers.

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